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Mechanistic Studies of Pain and Alcohol Dependence (R01)

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Mechanistic Studies of Pain and Alcohol Dependence (R01)

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Programming Grants to Accompany NEH on the Road Exhibitions

 

Deadline :  1-7-2018

Funding Opportunity :  PA-15-026

CFDA :  93.273|93.279|000000

Agency :  Department of Health and Human Services

Contact :  NIH OER Webmaster
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Eligibility :  State Governments
County Governments
City or Township Governments
Special District Governments
Independent School Districts
Public and State Controlled Institutions of Higher Education
Native American Tribal Governments (Federally recognized)
Public Housing Authorities/Indian Housing Authorities
Native American Tribal Organizations (other than Federally recognized tribal governments)
Nonprofits Having a 501 (c) (3) Status with the IRS (other than institutions of higher education)
Nonprofits that do not have a 501 (c) (3) status with the IRS (other than institutions of higher education)
Private institutions of higher education
For-profit organizations other than small business
Small businesses
Others

Details :  
This Funding Opportunity Announcement (FOA) encourages applications that propose to conduct mechanistic studies on the relationship between excessive alcohol drinking, alcohol dependence and pain. An association between chronic pain conditions and alcohol dependence has been revealed in numerous studies with episodes of alcohol abuse antedating chronic pain in some people and alcohol dependence emerging after the onset of chronic pain in others. Pain transmission and alcohols reinforcing effects share overlapping neural substrates giving rise to the possibility that chronic pain states significantly affect alcohol use patterns and promote the development of dependence and addiction. In addition, long term alcohol intoxication and alcohol dependence induce pain symptoms and may exacerbate chronic pain arising from other sources. The objective of this FOA is to understand genetic, pharmacological and learning mechanisms underlying the association between the propensity to drink excessively alcohol and pain responses.

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